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Increasing Efficacy for Lung Cancer Chemotherapeutics: Targeted Drug Delivery via the Protocell
Positive Binding of EGF Targeted Protocell
Figure 2: A549 cell line: Positive binding of EGF targeted protocell (no cargo in the protocell) on positive control A549 cells displayed on the left side. No binding of the non-targeted protocell group on A549 cells, displayed in the middle. No binding on the A549 cells when no treatment was added displayed on the left side. The stains seen in the confocal images above correspond as follows: Dapi nuclear stain (contained in the VECTASHIELD HardSet Mounting Medium with DAPI), Invitrogen CellTracker Green CMFDA the cytosol, Thermo Scientific Dylight 633 red the silica in the protocell. All images are 63x z-stack-maximum intensity projection
Credits: Annikka Jensen, University of New Mexico
