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Stochastic Modeling and Simulation of Cell Polarization During Mating in Budding Yeast

Polarisome Fragmentation and Scanning

Polarisome Fragmentation and Scanning

Earlier work by Yi demonstrated polarisome fragmentation and scanning. (A) Spa2-GFP cells treated with LatA show multiple polarisomes (top). Washing away the LatA collapses the polarisome fragments into a single structure (bottom) (B) Spa2-mCherry (red) can be seen scanning along the polarized front edge dened by Ste20-GFP in a low-factor gradient. Scale bar = 10 m.

Credits: Tau-Mu Yi, Department of Developmental Cell Biology, University of California, Irvine